Formerly International Journal of Basic and Applied Agricultural Research

Comprehensive case report of a mast cell tumor in a dog: clinical, cytological and histopathological analysis

SWASTI SHARMA, SONALI MISHRA and GAURAV JOSHI
Pantnagar Journal of Research, Volume - 23, Issue - 2 ( May-August 2025)

Published: 2025-09-01

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Abstract


This case describes a mast cell tumor (MCT) in an 11-year-old male dog presented with a history of 5-6 years old pendulous mass (8-10 cm diameter) with a firm base and ulcerated apex, located between the forelimbs and at the level of sternum. Fine needle aspiration cytology of the tumor revealed characteristic features of mast cell tumors, such as pleomorphic round cells with coarse basophilic cytoplasmic granules, hyperchromatic nuclei, prominent nucleoli, and an increased nuclear-to-cytoplasmic ratio, which were found consistent with the histopathological findings. Additionally, toluidine blue staining was used for the identification of mast cells. This case underscores the typical clinical presentation, cytological characteristics, and histopathological findings associated with mast cell tumors in dogs, illustrating the importance of both cytological and histopathological evaluation in diagnosing and managing MCTs.


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